Characterization of natural killer cells in patients with chronic rhinosinusitis

Chronic rhinosinusitis (CRS) is a heterogeneous disease. Possibilities for subclassification exist via the phenotype and by endotyping based on inflammatory infiltrate in local tissue. As an interesting component of innate immune defense, cytotoxic cytokine-producing natural killer cells (NK) as tissue-based can have direct influence pathogenesis. Thus, aim this work was precise characterization these patients with CRS.